Courtney Penniman transitioned from female to male in February 2012. He now lives comfortably as a man while helping other trans people who struggle with gender dysphoria. There are medical theories about why people are transgender. Some speculate that fluctuations or imbalances in hormones or the use of certain medications during pregnancy may cause intersex or transgender conditions. Other research indicates that there are links between transgender identity and brain structure. At this time, research has not come up with a definitive answer.